Concept information
Preferred term
Tretinoin
Type
-
mesh:Descriptor
Definition
- An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
Broader concept
Narrower concepts
Synonym(s)
- 13497-05-7 (Na salt)
- 22232-80-0 (K salt)
- 302-79-4 (Tretinoin)
- 5688UTC01R
- 75980-27-7 (Zn salt)
- all-trans-Retinoic Acid
- Retinoic acid
- Retinoic Acid
- trans-Retinoic Acid
- Vitamin A Acid
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Pharmacological Action(s)
In other languages
-
French
-
13497-05-7 (Na salt)
-
22232-80-0 (K salt)
-
302-79-4 (Tretinoin)
-
5688UTC01R
-
75980-27-7 (Zn salt)
-
Acide rétinoïque tout trans
-
Acide tout trans rétinoïque
-
Retinoic acid
-
Vitamine A acide
URI
http://data.loterre.fr/ark:/67375/JVR-JS1888SW-1
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