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... > Amino Acids, Peptides, and Proteins > Proteins > Viral Proteins > Retroviridae Proteins > Human Immunodeficiency Virus Proteins > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
... > Amino Acids, Peptides, and Proteins > Proteins > Viral Proteins > Retroviridae Proteins > Gene Products, env > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
... > Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Membrane Glycoproteins > Viral Envelope Proteins > Gene Products, env > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
... > Carbohydrates > Glycoconjugates > Glycoproteins > Membrane Glycoproteins > Viral Envelope Proteins > Gene Products, env > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Glycoproteins > Viral Envelope Proteins > Gene Products, env > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
... > Amino Acids, Peptides, and Proteins > Proteins > Viral Proteins > Viral Structural Proteins > Viral Envelope Proteins > Gene Products, env > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
... > Amino Acids, Peptides, and Proteins > Proteins > Polyproteins > Gene Products, env > env Gene Products, Human Immunodeficiency Virus > HIV Envelope Protein gp120
Biological Factors > Antigens > Antigens, Viral > HIV Antigens > HIV Envelope Protein gp120

Preferred term

HIV Envelope Protein gp120  

Type

  • mesh:Descriptor

Definition

  • External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.

Broader concept

Related concepts

Synonym(s)

  • Envelope Glycoprotein gp120, HIV
  • env Protein gp120, HIV
  • gp120 Envelope Glycoprotein, HIV
  • gp120(HIV)
  • HIV Envelope Glycoprotein gp120
  • HTLV-III gp120

Allowable Qualifier(s)

In other languages

  • Protéine d'enveloppe gp120 du VIH

    French

  • Glycoprotéine d'enveloppe gp120 du VIH
  • Glycoprotéine gp120 de l'enveloppe du VIH
  • gp120(VIH)
  • Protéine env gp120 du VIH
  • Protéine gp120 de l'enveloppe du VIH

URI

http://data.loterre.fr/ark:/67375/JVR-JGTGGXJN-T

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RDF/XML TURTLE JSON-LD Created 6/19/89, last modified 7/9/07