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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Poly-ADP-Ribose Binding Proteins > Werner Syndrome Helicase
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Poly-ADP-Ribose Binding Proteins > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Exonucleases > Exodeoxyribonucleases > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Deoxyribonucleases > Exodeoxyribonucleases > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Isomerases > DNA Helicases > RecQ Helicases > Werner Syndrome Helicase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Acid Anhydride Hydrolases > Adenosine Triphosphatases > DNA Helicases > RecQ Helicases > Werner Syndrome Helicase

Preferred term

Werner Syndrome Helicase  

Type

  • mesh:Descriptor

Definition

  • A DNA-dependent helicase and 3'-5' exonuclease. It has 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang and binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and HOLLIDAY JUNCTIONS. Mutations in the WRN gene are associated with WERNER SYNDROME.

Broader concept

Synonym(s)

  • RECQ3 Protein
  • RECQL2 Protein
  • Werner Syndrome ATP-Dependent Helicase
  • Werner Syndrome RecQ-Like Helicase

Allowable Qualifier(s)

In other languages

  • Werner syndrome helicase

    French

  • Hélicase ATP-dépendante du syndrome de Werner
  • Hélicase du syndrome de Werner
  • Hélicase du syndrome de Werner semblable à RecQ
  • Protéine RECQ3
  • Protéine RECQL2

URI

http://data.loterre.fr/ark:/67375/JVR-HHKM343N-2

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 5/24/17