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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > RNA-Binding Protein EWS
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > RNA-Binding Protein EWS
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Calmodulin-Binding Proteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > Heterogeneous-Nuclear Ribonucleoproteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > Heterogeneous-Nuclear Ribonucleoproteins > RNA-Binding Protein EWS

Preferred term

RNA-Binding Protein EWS  

Type

  • mesh:Descriptor

Definition

  • A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.

Broader concept

Related concepts

Synonym(s)

  • Ewing Sarcoma Breakpoint Region 1 Protein
  • Ewing Sarcoma Breakpointregion 1 Protein
  • EWS Protein
  • EWS Proto-Oncogene Protein
  • EWSR1 Protein
  • EWS RNA Binding Protein 1

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-GTZLS67Q-4

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RDF/XML TURTLE JSON-LD Created 7/3/02, last modified 6/29/17