Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

Concept information

Preferred term

Immunoglobulin Idiotypes  

Type

  • mesh:Descriptor

Definition

  • Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.

Synonym(s)

  • Idiotypes, Immunoglobulin
  • Ig Idiotypes

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-GH46W973-D

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/27/78, last modified 7/5/19