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Concept information

Macromolecular Substances > Multiprotein Complexes > Shelterin Complex > Telomeric Repeat Binding Protein 1

Preferred term

Telomeric Repeat Binding Protein 1  

Type

  • mesh:Descriptor

Definition

  • A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues. An alternatively spliced form of telomeric repeat binding protein 1. In human it lacks 20 amino acids.

Broader concept

Synonym(s)

  • TERF1 Protein
  • TRF1 Protein
  • TTAGGG Repeat Binding Factor 1

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-G9Z1DVDW-9

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RDF/XML TURTLE JSON-LD Created 7/3/02, last modified 5/10/21