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Concept information

Preferred term

Macrophage Colony-Stimulating Factor  

Type

  • mesh:Descriptor

Definition

  • A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

Synonym(s)

  • 81627-83-0
  • Colony-stimulating factor 1
  • Colony-Stimulating Factor 1
  • Colony-Stimulating Factor, Macrophage
  • CSF-1
  • CSF-M
  • M-CSF

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-G3BZVJ8K-G

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RDF/XML TURTLE JSON-LD Created 6/19/90, last modified 7/5/06