Skip to main content

Medical Subject Headings (thesaurus)

Search from vocabulary

align
annotate
download

Concept information

... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Protein Domains > Protein Interaction Domains and Motifs > src Homology Domains
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Tertiary > Protein Domains > Protein Interaction Domains and Motifs > src Homology Domains

Preferred term

src Homology Domains  

Type

  • mesh:Descriptor

Definition

  • Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.

Broader concept

Related concepts

Synonym(s)

  • SH Domains

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-FJ7FP68S-W

Download this concept:

RDF/XML TURTLE JSON-LD Created 1/6/95, last modified 5/31/16