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Concept information

Immune System Diseases > Autoimmune Diseases > Autoimmune Diseases of the Nervous System > Stiff-Person Syndrome
Nervous System Diseases > Autoimmune Diseases of the Nervous System > Stiff-Person Syndrome
Nervous System Diseases > Neuromuscular Diseases > Stiff-Person Syndrome
Nervous System Diseases > Central Nervous System Diseases > Spinal Cord Diseases > Stiff-Person Syndrome

Preferred term

Stiff-Person Syndrome  

Type

  • mesh:Descriptor

Definition

  • A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)

Broader concept

Synonym(s)

  • Congenital Stiff-Man Syndrome
  • Congenital Stiff-Person Syndrome
  • Moersch-Woltmann Syndrome
  • Startle Syndrome
  • Stiff-Baby Syndrome
  • Stiff-Man Syndrome
  • Stiffman Syndrome
  • Stiff-Trunk Syndrome

Allowable Qualifier(s)

In other languages

  • Syndrome de l'homme raide

    French

  • SHR (Syndrome de l'Homme Raide)
  • Syndrome de l'homme rigide
  • Syndrome de la personne raide
  • Syndrome de Moersch-Woltman

URI

http://data.loterre.fr/ark:/67375/JVR-DVPFD2T4-8

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RDF/XML TURTLE JSON-LD Created 4/29/91, last modified 1/20/16