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Concept information

Preferred term

CD4 Immunoadhesins  

Type

  • mesh:Descriptor

Definition

  • Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. These have potential use in the therapy of AIDS since they possess both the gp120-binding and HIV-blocking properties of rCD4 as well as the long plasma half-life and Fc receptor-binding functions of immunoglobulin.

Synonym(s)

  • Immunoadhesins, CD4

Pharmacological Action(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-D7DDB193-F

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RDF/XML TURTLE JSON-LD Created 7/12/91, last modified 6/25/10