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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Nuclear Receptor Coactivators > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Nuclear Receptor Coactivators > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > Nuclear Receptor Coactivators > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > Nuclear Receptor Coactivators > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Nuclear Receptor Coactivators > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

Preferred term

Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha  

Type

  • mesh:Descriptor

Definition

  • A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.

Broader concept

Synonym(s)

  • PGC-1-alpha Protein
  • PPARGC-1-alpha Protein
  • PPARGC1a Protein

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-CL3VMSQC-C

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 3/30/16