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Concept information

Preferred term

Lovastatin  

Type

  • mesh:Descriptor

Definition

  • A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver.

Broader concept

Narrower concepts

Synonym(s)

  • 6-Methylcompactin
  • 75330-75-5 (Lovastatin)
  • 9LHU78OQFD
  • Mevinolin
  • Monacolin K

In other languages

  • French

  • 75330-75-5 (Lovastatin)
  • 9LHU78OQFD

URI

http://data.loterre.fr/ark:/67375/JVR-BZNZHQJL-K

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