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Concept information

Preferred term

Receptor, Serotonin, 5-HT1D  

Type

  • mesh:Descriptor

Definition

  • A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.

Synonym(s)

  • 5-HT(1D) Receptor
  • 5-HT1D Receptor
  • 5-Hydroxytryptamine1D Receptor
  • Receptor, Serotonin 1D
  • Serotonin 1D Receptor
  • Serotonin 1D Receptors

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-BTT39N2J-4

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RDF/XML TURTLE JSON-LD Created 7/9/03, last modified 6/17/16