Concept information
...
Receptors, Cell Surface
Receptors, Neurotransmitter
Receptors, Serotonin
Receptors, Serotonin, 5-HT1
...
Receptors, Cell Surface
Receptors, G-Protein-Coupled
Receptors, Serotonin
Receptors, Serotonin, 5-HT1
Preferred term
Receptor, Serotonin, 5-HT1D
Type
-
mesh:Descriptor
Definition
- A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
Broader concept
Synonym(s)
- 5-HT(1D) Receptor
- 5-HT1D Receptor
- 5-Hydroxytryptamine1D Receptor
- Receptor, Serotonin 1D
- Serotonin 1D Receptor
- Serotonin 1D Receptors
Allowable Qualifier(s)
- administration & dosage (Qualifier)
- analysis (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- physiology (Qualifier)
- radiation effects (Qualifier)
- therapeutic use (Qualifier)
- ultrastructure (Qualifier)
In other languages
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French
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Récepteur 1D de la 5-hydroxytryptamine
-
Récepteur 1D de la sérotonine
-
Récepteur 5-HT 1D
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Récepteur 5-HT-1D
-
Récepteur 5-HT1D
URI
http://data.loterre.fr/ark:/67375/JVR-BTT39N2J-4
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