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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Tumor Necrosis Factor-alpha
Carbohydrates > Glycoconjugates > Glycoproteins > Tumor Necrosis Factor-alpha
Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Tumor Necrosis Factors > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Tumor Necrosis Factors > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Tumor Necrosis Factors > Tumor Necrosis Factor-alpha
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Tumor Necrosis Factor-alpha
Biological Factors > Intercellular Signaling Peptides and Proteins > Cytokines > Monokines > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Cytokines > Monokines > Tumor Necrosis Factor-alpha
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Cytokines > Monokines > Tumor Necrosis Factor-alpha

Preferred term

Tumor Necrosis Factor-alpha  

Type

  • mesh:Descriptor

Definition

  • Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

Broader concept

Related concepts

Synonym(s)

  • Cachectin
  • Cachectin-Tumor Necrosis Factor
  • TNF-alpha
  • TNFalpha
  • TNF Superfamily, Member 2
  • Tumor Necrosis Factor
  • Tumor Necrosis Factor Ligand Superfamily Member 2

Allowable Qualifier(s)

In other languages

  • Facteur de nécrose tumorale alpha

    French

  • Cachectine
  • Facteur alpha de nécrose tumorale
  • Facteur de nécrose tumorale
  • Ligand TNFSF2
  • Membre-2 de la superfamille des ligands TNF
  • Membre-2 de la superfamille des TNF ligands
  • Membre-2 de la superfamille du facteur de nécrose tumorale
  • Membre-2 de la superfamille du TNF
  • TNF (Tumor Necrosis Factor)
  • TNF alpha

URI

http://data.loterre.fr/ark:/67375/JVR-BSJWQ6M7-9

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RDF/XML TURTLE JSON-LD Created 5/8/87, last modified 6/20/17