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Concept information

Preferred term

Wnt-5a Protein  

Type

  • mesh:Descriptor

Definition

  • A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells.

Synonym(s)

  • Wingless-Type MMTV Integration Site Family, Member 5A
  • Wnt5a Protein

In other languages

  • French

  • Membre-5A de la famille de sites d'intégration de MMTV de type Wingless
  • Protéine Wnt5a

URI

http://data.loterre.fr/ark:/67375/JVR-BH9KM8K3-1

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RDF/XML TURTLE JSON-LD Created 7/8/16, last modified 4/15/16