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... > Genetic Phenomena > Gene Expression Regulation > Protein Modification, Translational > Protein Processing, Post-Translational > Unfolded Protein Response > Endoplasmic Reticulum-Associated Degradation
... > Genetic Phenomena > Gene Expression > Protein Biosynthesis > Protein Modification, Translational > Protein Processing, Post-Translational > Unfolded Protein Response > Endoplasmic Reticulum-Associated Degradation
... > Metabolism > Peptide Biosynthesis > Protein Biosynthesis > Protein Modification, Translational > Protein Processing, Post-Translational > Unfolded Protein Response > Endoplasmic Reticulum-Associated Degradation
... > Chemical Phenomena > Biochemical Phenomena > Peptide Biosynthesis > Protein Biosynthesis > Protein Modification, Translational > Protein Processing, Post-Translational > Unfolded Protein Response > Endoplasmic Reticulum-Associated Degradation

Preferred term

Endoplasmic Reticulum-Associated Degradation  

Type

  • mesh:Descriptor

Definition

  • A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.

Broader concept

Related concepts

Synonym(s)

  • ERAD Pathway

Allowable Qualifier(s)

In other languages

URI

http://data.loterre.fr/ark:/67375/JVR-B4BQBNPV-1

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RDF/XML TURTLE JSON-LD Created 6/24/11, last modified 6/23/16