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Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Dihydropyridines > 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
Heterocyclic Compounds > Heterocyclic Compounds, 1-Ring > Pyridines > Nicotinic Acids > 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
Heterocyclic Compounds > Acids, Heterocyclic > Nicotinic Acids > 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester

Preferred term

3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester  

Type

  • mesh:Descriptor

Definition

  • A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.

Synonym(s)

  • 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester
  • 71145-03-4
  • 97217-82-8 ((+-)-isomer)
  • 98625-26-4 ((-)-isomer)
  • 98791-67-4 ((+)-isomer)

Pharmacological Action(s)

In other languages

  • French

  • 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, methyl ester
  • 4-(2-(Trifluorométhyl)phényl)-2,6-diméthyl-5-nitro-1,4-dihydro-pyridine-3-carboxylate de méthyle
  • 4-(2-(Trifluorométhyl)phényl)-2,6-diméthyl-5-nitro-1,4-dihydronicotinate de méthyle
  • 4-(2-(Trifluorométhyl)phényl)-2,6-diméthyl-5-nitro-1,4-dihydropyridine-3-carboxylate de méthyle
  • 71145-03-4
  • 97217-82-8 ((+-)-isomer)
  • 98625-26-4 ((-)-isomer)
  • 98791-67-4 ((+)-isomer)

URI

http://data.loterre.fr/ark:/67375/JVR-B3S97GKG-S

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