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Concept information

... > clinical research > candidate treatment > candidate drug > drug class > antiviral > protease inhibitor > ritonavir

Terme préférentiel

ritonavir  

Définition

  • Ritonavir was originally developed as an inhibitor of HIV protease, one of a family of pseudo-C2-symmetric small molecule inhibitors. Ritonavir is now rarely used for its own antiviral activity but remains widely used as a booster of other protease inhibitors. More specifically, ritonavir is used to inhibit a particular enzyme, in intestines, liver, and elsewhere, that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4). (Wikipedia)

Concept générique

Créateur

  • Patricia Fener

Traductions

URI

http://data.loterre.fr/ark:/67375/C0X-W85D2LV8-N

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