Concept information
Término preferido
infection-associated enhanced disease
Definición
- Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication. Antiviral antibodies promote viral infection of target immune cells by exploiting the phagocytic FcγR or complement pathway. After interaction with the virus the antibody binds Fc receptors (FcR) expressed on certain immune cells or some of the complement proteins. (Wikipédia)
Concepto genérico
Etiquetas alternativas
- antibody-dependent enhancement
Creador
- Patricia Fener
En otras lenguas
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francés
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facilitation de l'infection par des anticorps
URI
http://data.loterre.fr/ark:/67375/C0X-GGJVKFJT-9
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